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Found 31 with Last Name = 'yim' and Initial = 'jh'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50374277(CHEMBL403094)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human recombinant PTP1B by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50340637(CHEMBL4163641)
Affinity DataIC50:  500nMAssay Description:Inhibition of PTP1B (1 to 298 residues) (unknown origin) using p-nitrophenylphosphate as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50294526(CHEMBL551842 | cid_73157 | lobaric acid)
Affinity DataIC50:  800nMAssay Description:Inhibition of PTP1B (1 to 298 residues) (unknown origin) using p-nitrophenylphosphate as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50294526(CHEMBL551842 | cid_73157 | lobaric acid)
Affinity DataIC50:  870nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50340635(CHEMBL4174317)
Affinity DataIC50:  900nMAssay Description:Inhibition of PTP1B (1 to 298 residues) (unknown origin) using p-nitrophenylphosphate as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50294527(3-(1-butyl-1,6-dimethoxy-3-oxo-1,3-dihydroisobenzo...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PTP1B (1 to 298 residues) (unknown origin) using p-nitrophenylphosphate as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50340636(SAKISACAULON A)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of PTP1B (1 to 298 residues) (unknown origin) using p-nitrophenylphosphate as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50294527(3-(1-butyl-1,6-dimethoxy-3-oxo-1,3-dihydroisobenzo...)
Affinity DataIC50:  2.48E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of PTP1B (1 to 298 residues) (unknown origin) using p-nitrophenylphosphate as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50294530(CHEMBL559457 | methyl 8-hydroxy-3-methoxy-11-oxo-1...)
Affinity DataIC50:  3.02E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  3.08E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  3.08E+3nMAssay Description:Inhibition of human recombinant PTP1B using p-nitrophenyl phosphate as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50374277(CHEMBL403094)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50374279(OHIOENSIN A)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50374280(CHEMBL403411)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50294525(3-butyl-7-(2,4-dihydroxy-6-pentylphenoxy)-3,5-dime...)
Affinity DataIC50:  6.86E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50294531(CHEMBL562970 | methyl 3,8-dimethoxy-11-oxo-1-penta...)
Affinity DataIC50:  7.42E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50374278(CHEMBL465069)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50036279(CHEMBL3353037)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of human recombinant PTP1B assessed as reduction in pNPP substrate hydrolysis incubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50036280(CHEMBL3353035)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of human recombinant PTP1B assessed as reduction in pNPP substrate hydrolysis incubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50402672(CHEMBL2207339)
Affinity DataIC50:  1.39E+4nMAssay Description:Inhibition of human recombinant PTP1B using p-nitrophenyl phosphate as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50251341(CHEMBL514108 | Usimine A)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50056923((+)-usnic acid | (9bR)-2,6-diacetyl-3,7,9-trihydro...)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50251356(CHEMBL457491 | CHEMBL514578 | Usimine B)
Affinity DataIC50:  2.32E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50251356(CHEMBL457491 | CHEMBL514578 | Usimine B)
Affinity DataIC50:  2.77E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50056919(3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl 3...)
Affinity DataIC50:  6.35E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50241521(CHEMBL470649 | methyl 3-formyl-2,4-dihydroxy-6-met...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50294528(CHEMBL454431 | methyl 2,4-dihydroxy-6-methylbenzoa...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50294529(1-(2,6-dihydroxy-4-methoxy-3-methylphenyl)ethanone...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed