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Found 21 with Last Name = 'yoshimura' and Initial = 'm'
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492526(CHEMBL2407616)
Affinity DataKi:  0.895nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492522(CHEMBL2407622)
Affinity DataKi:  0.895nMAssay Description:Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiographyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50122787(2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyr...)
Affinity DataKi:  7.20nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492518(Florbetapir | US10906900, AV45)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492519(CHEMBL2407615)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492516(CHEMBL2407621)
Affinity DataKi:  16nMAssay Description:Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiographyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50390102(CHEMBL2069433)
Affinity DataKi:  17nMAssay Description:Binding affinity to human Tau aggregates after 30 mins by Thioflavin-S-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492523(CHEMBL2407623)
Affinity DataKi:  111nMAssay Description:Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiographyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492523(CHEMBL2407623)
Affinity DataKi:  111nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50390103(CHEMBL2069432)
Affinity DataKi:  112nMAssay Description:Binding affinity to human Tau aggregates after 30 mins by Thioflavin-S-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492520(CHEMBL2407624)
Affinity DataKi: >242nMAssay Description:Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiographyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492517(CHEMBL2407618)
Affinity DataKi: >242nMAssay Description:Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiographyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492521(CHEMBL2407617)
Affinity DataKi: >242nMAssay Description:Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiographyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492520(CHEMBL2407624)
Affinity DataKi:  242nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50390104(CHEMBL2069431)
Affinity DataKi:  599nMAssay Description:Binding affinity to human Tau aggregates after 30 mins by Thioflavin-S-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492524(CHEMBL2407625)
Affinity DataKi:  758nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492525(CHEMBL2407626)
Affinity DataKi:  1.18E+3nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50390105(CHEMBL2069430)
Affinity DataKi:  1.43E+3nMAssay Description:Binding affinity to human Tau aggregates after 30 mins by Thioflavin-S-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50434484(CHEMBL2385165)
Affinity DataKd:  300nMAssay Description:Binding affinity to recombinant human tau (441 amino acid residues) aggregates expressed in Escherichia coli assessed as apparent dissociation consta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50434483(CHEMBL2385164)
Affinity DataKd:  450nMAssay Description:Binding affinity to recombinant human tau (441 amino acid residues) aggregates expressed in Escherichia coli assessed as apparent dissociation consta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50434482(CHEMBL2385163)
Affinity DataKd:  2.36E+3nMAssay Description:Binding affinity to recombinant human tau (441 amino acid residues) aggregates expressed in Escherichia coli assessed as apparent dissociation consta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed