TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: 279nMAssay Description:Inhibition of human intestinal CE1 using O-nitrophenyl acetate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: 381nMAssay Description:Inhibition of human intestinal CE1 using O-nitrophenyl acetate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: 437nMAssay Description:Inhibition of human intestinal CE1 using O-nitrophenyl acetate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: 756nMAssay Description:Inhibition of human intestinal CE1 using O-nitrophenyl acetate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: 1.03E+3nMAssay Description:Inhibition of human intestinal CE1 using O-nitrophenyl acetate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: 1.24E+3nMAssay Description:Inhibition of human intestinal CE1 using O-nitrophenyl acetate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human intestinal CE1 using O-nitrophenyl acetate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human intestinal CE1 using O-nitrophenyl acetate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human intestinal CE1 using O-nitrophenyl acetate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human intestinal CE1 using O-nitrophenyl acetate as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine
Curated by ChEMBL
Duke University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of ATM (unknown origin)More data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine
Curated by ChEMBL
Duke University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of ATM (unknown origin)More data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine
Curated by ChEMBL
Duke University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human ATM using p53 as substrate preincubated for 10 mins by ELISAMore data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine
Curated by ChEMBL
Duke University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of flag-tagged ATM (unknown origin) using p53 as substrate by ELISAMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine
Curated by ChEMBL
Duke University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of ATM in human U2OS cells assessed as inhibition of p53 phosphorylation at Ser15 residueMore data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine
Curated by ChEMBL
Duke University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 1 (49 to 170 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine
Curated by ChEMBL
Duke University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 1 (49 to 170 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine
Curated by ChEMBL
Duke University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assayMore data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine
Curated by ChEMBL
Duke University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assayMore data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine
Curated by ChEMBL
Duke University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine
Curated by ChEMBL
Duke University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assayMore data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine
Curated by ChEMBL
Duke University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair