Found 13 with Last Name = 'young' and Initial = 'dw' 
Affinity DataKi: 24nMAssay Description:To determine the Ki values of active compounds, 25 nM Mpro was mixed with increasing concentrations of compounds (from 4 nM to 4,000 nM with twofold ...More data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:To determine the Ki values of active compounds, 25 nM Mpro was mixed with increasing concentrations of compounds (from 4 nM to 4,000 nM with twofold ...More data for this Ligand-Target Pair
Affinity DataKi: 65nMAssay Description:To determine the Ki values of active compounds, 25 nM Mpro was mixed with increasing concentrations of compounds (from 4 nM to 4,000 nM with twofold ...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 2.40E+3nMAssay Description:To determine the Ki values of active compounds, 25 nM Mpro was mixed with increasing concentrations of compounds (from 4 nM to 4,000 nM with twofold ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of SARS-CoV-2 replication in VERO E6 and HEK hACE2 cells was measured using an xCELLigence RTCA HT Analyzer (Agilent Technologies), tracki...More data for this Ligand-Target Pair
Affinity DataIC50: 5.19E+3nMAssay Description:Inhibition of SARS-CoV-2 replication in VERO E6 and HEK hACE2 cells was measured using an xCELLigence RTCA HT Analyzer (Agilent Technologies), tracki...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Institute Of Harvard And Mit
Curated by ChEMBL
Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant full-length N-terminal GST tagged human GSK-3 beta expressed in baculovirus infected Sf9 insect cells using GSM as substrat...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Institute Of Harvard And Mit
Curated by ChEMBL
Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 3.22E+5nMAssay Description:Inhibition of recombinant full-length N-terminal GST tagged human GSK-3 beta expressed in baculovirus infected Sf9 insect cells using GSM as substrat...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataEC50: 5.70E+3nMAssay Description:Activation of wild type human N-terminal full length SIRT6 deacetylation (8 to 533 residues) expressed in Escherichia coli BL21 (DE3) expression syst...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Institute Of Harvard And Mit
Curated by ChEMBL
Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataKd: 6.00E+5nMAssay Description:Binding affinity to GSK-3 beta (unknown origin) after 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Institute Of Harvard And Mit
Curated by ChEMBL
Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataKd: 9.00E+3nMAssay Description:Binding affinity to GSK-3 beta (unknown origin) after 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ULK1(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataKd: 290nMAssay Description:Binding affinity to wild type ULK1 (unknown origin) expressed in HEK293T cells assessed as dissociation constant measured after 8 mins by SPR analysi...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataEC50: 3.80E+4nMAssay Description:Activation of human SIRT6 using acetylated histone H3K9 as peptide substrateMore data for this Ligand-Target Pair
