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Found 46 with Last Name = 'zender' and Initial = 'm'
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50028166(CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...)
Affinity DataIC50:  14.6nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human placental CYP19 using androstenedione as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334187(3,4-Difluoro-N-(pyridin-3-yl)benzamide | CHEMBL164...)
Affinity DataIC50:  53.5nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334191(4-Chloro-N-(pyridin-3-yl)benzamide | CHEMBL1645408)
Affinity DataIC50:  65nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50028166(CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334189(4-Cyano-N-(pyridin-3-yl)benzamide | CHEMBL1645412)
Affinity DataIC50:  78nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334192(4-Fluoro-N-(pyridin-3-yl)benzamide | CHEMBL1645407)
Affinity DataIC50:  82nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334190(4-Bromo-N-(pyridin-3-yl)benzamide | CHEMBL1645409)
Affinity DataIC50:  104nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334188(4-Nitro-N-(pyridin-3-yl)benzamide | CHEMBL1645413)
Affinity DataIC50:  145nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334186(2,4,5-trifluoro-N-(pyridin-3-yl)benzamide | CHEMBL...)
Affinity DataIC50:  166nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using progesterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334187(3,4-Difluoro-N-(pyridin-3-yl)benzamide | CHEMBL164...)
Affinity DataIC50:  5.92E+3nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334189(4-Cyano-N-(pyridin-3-yl)benzamide | CHEMBL1645412)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334191(4-Chloro-N-(pyridin-3-yl)benzamide | CHEMBL1645408)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334192(4-Fluoro-N-(pyridin-3-yl)benzamide | CHEMBL1645407)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334186(2,4,5-trifluoro-N-(pyridin-3-yl)benzamide | CHEMBL...)
Affinity DataIC50:  1.61E+4nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334190(4-Bromo-N-(pyridin-3-yl)benzamide | CHEMBL1645409)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334188(4-Nitro-N-(pyridin-3-yl)benzamide | CHEMBL1645413)
Affinity DataIC50:  2.48E+4nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50106197(3-Bromo-benzamide | CHEMBL122690)
Affinity DataKd:  6.80E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440121(CHEMBL2426237 | US11634391, Compound 117)
Affinity DataKd:  6.50E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440130(CHEMBL1383520 | US11634391, Compound 168)
Affinity DataKd:  4.50E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440130(CHEMBL1383520 | US11634391, Compound 168)
Affinity DataKd:  3.70E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440131(CHEMBL2426236)
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440132(CHEMBL154085 | Naphthalene-2-Carboxylic Acid Amide)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440124(CHEMBL2426232)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440133(CHEMBL2426225)
Affinity DataKd:  900nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440132(CHEMBL154085 | Naphthalene-2-Carboxylic Acid Amide)
Affinity DataKd:  800nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM98803(EN300-42473 | US8487093, 193)
Affinity DataKd:  6.80E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440129(CHEMBL2426231)
Affinity DataEC50:  7.50E+3nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440124(CHEMBL2426232)
Affinity DataEC50:  7.50E+3nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50106197(3-Bromo-benzamide | CHEMBL122690)
Affinity DataKd:  7.60E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440128(CHEMBL1545380)
Affinity DataKd:  8.50E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM98803(EN300-42473 | US8487093, 193)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440128(CHEMBL1545380)
Affinity DataKd:  1.07E+4nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440122(CHEMBL2426235)
Affinity DataKd:  1.24E+4nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440127(CHEMBL2426238)
Affinity DataKd:  1.29E+4nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440126(CHEMBL2426233)
Affinity DataEC50:  1.78E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440125(CHEMBL2426228)
Affinity DataEC50:  2.67E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440124(CHEMBL2426232)
Affinity DataEC50:  3.85E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in pqs gene-deficient Pseudomonas aeruginosa PA14 by beta-galactosidase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440123(CHEMBL2426234)
Affinity DataEC50:  4.65E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440122(CHEMBL2426235)
Affinity DataEC50:  5.78E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440121(CHEMBL2426237 | US11634391, Compound 117)
Affinity DataEC50:  1.01E+5nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440120(CHEMBL1393516 | US11634391, Compound 156)
Affinity DataKd:  2.00E+5nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetQuinolone signal response protein(Pseudomonas aeruginosa PAO1)
Helmholtz-Institute For Pharmaceutical Research Saarland

LigandPNGBDBM185154(AC30341 (3))
Affinity DataKd:  1.96E+4nMT: 2°CAssay Description:ITC titrations were performed using an ITC200 instrument (Microcal Inc.,Malvern). DMSO stock solutions (20 mM) of fragments were diluted 1:20 (v/v) i...More data for this Ligand-Target Pair
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa PA14)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440134(CHEMBL2426244)
Affinity DataKd:  210nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetQuinolone signal response protein(Pseudomonas aeruginosa PAO1)
Helmholtz-Institute For Pharmaceutical Research Saarland

LigandPNGBDBM185153(CC41801 (1))
Affinity DataKd:  900nMT: 2°CAssay Description:ITC titrations were performed using an ITC200 instrument (Microcal Inc.,Malvern). DMSO stock solutions (20 mM) of fragments were diluted 1:20 (v/v) i...More data for this Ligand-Target Pair