Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 53 hits for monomerid = 12024,12025,12026,12027,12028,12029,123786,12024,12025,12026,12027,12028,12029,123786   

TargetCyclin-dependent kinase 9(Human)
Institute of Experimental Botany Ascr and Palacky University

LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 280nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palack�

Curated by ChEMBL
LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 280nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palack�

Curated by ChEMBL
LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 350nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palack�

Curated by ChEMBL
LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataKi:  350nMAssay Description:Inhibition of CDK9/Cyclin T (1 to 330 amino acid residues) (unknown origin) by differential scanning fluorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 9(Human)
Institute of Experimental Botany Ascr and Palacky University

LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 350nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 450nMAssay Description:Inhibition of CDK4/cyclin D1 (unknown origin) expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Institute of Experimental Botany Ascr and Palacky University

LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 454nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Institute of Experimental Botany Ascr and Palacky University

LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 549nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 550nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin) expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Institute of Experimental Botany Ascr and Palacky University

LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 1.33E+3nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palack�

Curated by ChEMBL
LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 1.50E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palack�

Curated by ChEMBL
LigandPNGBDBM12025(4-[(E)-2-(2-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 5.60E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palack�

Curated by ChEMBL
LigandPNGBDBM12026(4-[(E)-2-(3-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 1.24E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Institute of Experimental Botany Ascr and Palacky University

LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 1.35E+4nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 1.35E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Institute of Experimental Botany Ascr and Palacky University

LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 1.49E+4nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Palack�

Curated by ChEMBL
LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of CDK7/cyclin H (unknown origin) expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palack�

Curated by ChEMBL
LigandPNGBDBM12024(4-[(E)-2-phenyldiazen-1-yl]-1H-pyrazole-3,5-diamin...)
Affinity DataIC50: 1.50E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12025(4-[(E)-2-(2-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 1.60E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 2.00E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
Institute of Experimental Botany Ascr and Palacky University

LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 2.00E+4nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM12025(4-[(E)-2-(2-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 2.20E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palack�

Curated by ChEMBL
LigandPNGBDBM12029({2-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl...)
Affinity DataIC50: 2.60E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Palack�

Curated by ChEMBL
LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 2.60E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Institute of Experimental Botany Ascr and Palacky University

LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 2.60E+4nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
LigandPNGBDBM12025(4-[(E)-2-(2-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 4.20E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 4.40E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Institute of Experimental Botany Ascr and Palacky University

LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 4.40E+4nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 5.10E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 5.60E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12026(4-[(E)-2-(3-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 6.80E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataKi:  6.90E+4nMAssay Description:Inhibition of CDK2/Cyclin A (174 to 432 amino acid residues) (unknown origin) by differential scanning fluorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Palacky University

LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 6.90E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM12026(4-[(E)-2-(3-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 7.00E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Palack�

Curated by ChEMBL
LigandPNGBDBM12025(4-[(E)-2-(2-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 7.70E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12029({2-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl...)
Affinity DataIC50: 7.70E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Palack�

Curated by ChEMBL
LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 8.20E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Palacky University

LigandPNGBDBM12025(4-[(E)-2-(2-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 8.80E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12026(4-[(E)-2-(3-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12029({2-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12024(4-[(E)-2-phenyldiazen-1-yl]-1H-pyrazole-3,5-diamin...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12024(4-[(E)-2-phenyldiazen-1-yl]-1H-pyrazole-3,5-diamin...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12029({2-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Palacky University

LigandPNGBDBM12024(4-[(E)-2-phenyldiazen-1-yl]-1H-pyrazole-3,5-diamin...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Palacky University

LigandPNGBDBM12026(4-[(E)-2-(3-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Palacky University

LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Palacky University

LigandPNGBDBM12029({2-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Palack�

Curated by ChEMBL
LigandPNGBDBM12024(4-[(E)-2-phenyldiazen-1-yl]-1H-pyrazole-3,5-diamin...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
Displayed 1 to 50 (of 53 total )  |  Next  |  Last  >>