Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50025835,50166432,50166433,50166435,50308840,50025835,50166432,50166433,50166435,50308840   

LigandPNGBDBM50025835(CHEMBL592291)
Affinity DataIC50: 30nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50308840(5-[2-Hydroxy-5-(1H-pyrrol-2-yl)-phenyl]-1,1-dioxo-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50308840(5-[2-Hydroxy-5-(1H-pyrrol-2-yl)-phenyl]-1,1-dioxo-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50166435(5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-...)
Affinity DataKi:  2.40E+3nM IC50: 4.80E+3nMpH: 7.0Assay Description:Assays for the reversible inhibition of PTP1B (72 nM) contained the test compound(2a, 2b, 5a, or 5b) in Bis-Tris (50 mM), NaCl (100 mM), EDTA (2 mM),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2017
Entry Details Article
PubMed
LigandPNGBDBM50166435(5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-...)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibitory concentration against Protein tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50166435(5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50166435(5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50166432(5-Biphenyl-3-yl-1,1-dioxo-1lambda*6*-[1,2,5]thiadi...)
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibitory concentration against Protein tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50166433(5-(2-Methoxy-phenyl)-1,1-dioxo-1lambda*6*-[1,2,5]t...)
Affinity DataIC50: 1.38E+5nMAssay Description:Inhibitory concentration against Protein tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed