Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 42 hits for monomerid = 50048093,50272147,50336202,50336204,50370453,50048093,50272147,50336202,50336204,50370453   

TargetGalectin-8(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336204(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to human galectin-8 component 1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGalectin-8(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336204(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to human galectin-8 component 1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGalectin-8(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336204(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  24.6nMAssay Description:Binding affinity to human galectin-8 component 2 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGalectin-8(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336202(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  31.3nMAssay Description:Binding affinity to human galectin-8 component 2 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGalectin-8(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336202(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  36.9nMAssay Description:Binding affinity to human galectin-8 component 1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGalectin-8(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336202(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  36.9nMAssay Description:Binding affinity to human galectin-8 component 1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGalectin-4(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336202(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  58nMAssay Description:Binding affinity to human galectin-4 component 2 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGalectin-4(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336204(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  85nMAssay Description:Binding affinity to human galectin-4 component 2 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGalectin-4(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336204(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  85nMAssay Description:Binding affinity to human galectin-4 component 2 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGalectin-4(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336204(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  136nMAssay Description:Binding affinity to human galectin-4 component 1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGalectin-4(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336202(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  304nMAssay Description:Binding affinity to human galectin-4 component 1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGalectin-4(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336202(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  304nMAssay Description:Binding affinity to human galectin-4 component 1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGalectin-3(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336204(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  1.06E+3nMAssay Description:Binding affinity to human galectin-3 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGalectin-3(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336204(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  1.06E+3nMAssay Description:Binding affinity to human galectin-3 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGalectin-3(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336202(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  1.43E+3nMAssay Description:Binding affinity to human galectin-3 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGalectin-3(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50336202(12-Mercaptododecyl-beta-D-galactopyranosyl-(1->4)-...)
Affinity DataKd:  1.43E+3nMAssay Description:Binding affinity to human galectin-3 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTrans-sialidase [3-643](Trypanosoma cruzi)
Universidade Federal Do Rio De Janeiro

LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataKd:  1.50E+4nMT: 2°CAssay Description:Solutions of TS, TSY342H, and TSD247A in 20 mM Tris-HCl were exchanged with deuterated PBS using four cycles of concentration with Amicon Ultra (50,0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetGalectin-9(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataKd:  2.30E+4nMAssay Description:Antagonist activity against human galectin 9 N-terminal domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetGalectin-9(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  2.30E+4nMAssay Description:Binding affinity to galectin 9N terminal domain at 0 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-8(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  3.79E+4nMAssay Description:Binding affinity to N-terminal domain of human galectin-8 (8-154 residues) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTrans-sialidase [3-643,Y342H](Trypanosoma cruzi)
Universidade Federal Do Rio De Janeiro

LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataKd:  5.20E+4nMT: 2°CAssay Description:Solutions of TS, TSY342H, and TSD247A in 20 mM Tris-HCl were exchanged with deuterated PBS using four cycles of concentration with Amicon Ultra (50,0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetGalectin-8(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataKd:  6.20E+4nMAssay Description:Antagonist activity against human galectin 8 N-terminal domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetGalectin-8(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  6.20E+4nMAssay Description:Binding affinity to galectin 8N terminal domain at 20 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGalectin-8(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  9.10E+4nMAssay Description:Binding affinity to human galactin-8 N terminal domain assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGalectin-3(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  9.26E+4nMAssay Description:Inhibition of human recombinant wild type galectin 3 after 60 mins by surface plasmon resonance immunosensor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2016
Entry Details Article
PubMed
TargetGalectin-7(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataKd:  1.10E+5nMAssay Description:Antagonist activity against human galectin 7 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetGalectin-7(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  1.10E+5nMAssay Description:Binding affinity to galectin 7 at 0 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-3(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  1.10E+5nMAssay Description:Binding affinity to galectin 3 at 20 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-3(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50272147((2S,3R,4S,5R,6R)-2-((2R,3S,4R,5R,6R)-6-(6-((2S,3S,...)
Affinity DataIC50: 1.63E+5nMAssay Description:Inhibition of galectin 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataKd:  1.90E+5nMAssay Description:Antagonist activity against human galectin 1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetGalectin-3(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataKd:  2.20E+5nMAssay Description:Antagonist activity against human galectin 3 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetGalectin-3(Mouse)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  2.22E+5nMAssay Description:Dissociation constant for mouse Galectin-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetGalectin-3(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  2.30E+5nMAssay Description:Binding affinity to galectin-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetGalectin-3(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  2.31E+5nMAssay Description:Binding affinity to human galactin-3 assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  4.20E+5nMAssay Description:Binding affinity to galectin 1 at 20 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of recombinant galectin 1 in human O type red blood cells by hemagglutinination assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetGalectin-3(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of recombinant galectin 3 in human O type red blood cells by hemagglutinination assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetGalectin-3(Mouse)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of galectin-3 in C57BL/6 mouse jejunum using SK-5100 as substrate incubated for 30 mins by VAA staining based microscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetGalectin(Chicken)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataIC50: 1.10E+6nMAssay Description:Inhibition of binding of biotinylated chicken galectin-3 to surface immobilized asialofetuin by solid phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-galactoside-binding lectin(Chicken)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataIC50: 4.00E+6nMAssay Description:Inhibition of binding of biotinylated chicken galectin-1B to surface immobilized asialofetuin by solid phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGalectin(Chicken)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataIC50: 4.50E+6nMAssay Description:Inhibition of binding of biotinylated truncated chicken galectin-3 to surface immobilized asialofetuin by solid phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataIC50: 7.40E+6nMAssay Description:Inhibition of asialofetuin binding to human recombinant Gal-1 transfected in Escherichia coli BL21 (DE3) incubated for 2 hrs by competitive solid-pha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed