Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50197886,50197887,50197889,50197892,50313480,50197886,50197887,50197889,50197892,50313480   

TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313480(4-(cyclohexylamino)-6-(piperazin-1-yl)-1,3,5-triaz...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCathepsin S(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197886(CHEMBL3936923)
Affinity DataIC50: 17nMAssay Description:Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin S(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197889(CHEMBL3922171)
Affinity DataIC50: 23nMAssay Description:Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50197886(CHEMBL3936923)
Affinity DataIC50: 23nMAssay Description:Inhibition of human cathepsin K expressed in Pichia pastoris using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin S(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197892(CHEMBL3949917)
Affinity DataIC50: 23nMAssay Description:Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin S(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197887(CHEMBL3899928)
Affinity DataIC50: 23nMAssay Description:Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197887(CHEMBL3899928)
Affinity DataIC50: 45nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin B(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197886(CHEMBL3936923)
Affinity DataIC50: 57nMAssay Description:Inhibition of human cathepsin B using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50197889(CHEMBL3922171)
Affinity DataIC50: 60nMAssay Description:Inhibition of human cathepsin K expressed in Pichia pastoris using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50197887(CHEMBL3899928)
Affinity DataIC50: 68nMAssay Description:Inhibition of human cathepsin K expressed in Pichia pastoris using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50197892(CHEMBL3949917)
Affinity DataIC50: 80nMAssay Description:Inhibition of human cathepsin K expressed in Pichia pastoris using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin B(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197887(CHEMBL3899928)
Affinity DataIC50: 136nMAssay Description:Inhibition of human cathepsin B using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin S(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50313480(4-(cyclohexylamino)-6-(piperazin-1-yl)-1,3,5-triaz...)
Affinity DataIC50: 158nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin B(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50313480(4-(cyclohexylamino)-6-(piperazin-1-yl)-1,3,5-triaz...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant cathepsin B by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50313480(4-(cyclohexylamino)-6-(piperazin-1-yl)-1,3,5-triaz...)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of human recombinant cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed