Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50265379,50304739,50304740,50304741,50398812,50441243,50265379,50304739,50304740,50304741,50398812,50441243   

TargetGlutamate carboxypeptidase 2(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50441243(CHEMBL2431334)
Affinity DataKd:  143nMAssay Description:Binding affinity to PSMA in human LNCaP cells after 1 hr by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50398812(CHEMBL2177511)
Affinity DataKi:  392nMAssay Description:Binding affinity to NAALADaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50265379((S)-2-(3-((S)-1-Carboxy-5-(3-iodobenzylamino)penty...)
Affinity DataIC50: 443nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50304739(2-(3-(1-Carboxy-2-(4-hydroxyphenyl)ethyl)ureido)-4...)
Affinity DataKi:  700nMAssay Description:Inhibition of glutamate carboxypeptidase 2 in human LNCaP cells by fluorescence based NAALADase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50304740(2-(3-(1-Carboxy-2-(4-hydroxy-3-iodophenyl)ethyl)ur...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of glutamate carboxypeptidase 2 in human LNCaP cells by fluorescence based NAALADase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50304741((S)-3-(3-Hydroxyphenyl)-2-(3-(1-methoxy-4-methyl-1...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of glutamate carboxypeptidase 2 in human LNCaP cells by fluorescence based NAALADase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed