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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Cytochrome P450 1B1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50242377
(CHEMBL448060 | isoimperatorin)
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Affinity Data
Ki: 6.00E+3nM
Assay Description:
Competitive inhibition of CYP1B1 (unknown origin) expressed in yeast microsomes using (-)benzo[a]pyrene-7R-trans-7,8-dihyrodiol (B[a]P-7,8-diol) as s...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
KEGG
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PC sid
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Article
PubMed
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Target
Amine oxidase [flavin-containing] A
(Homo sapiens (Human))
Sunchon National University
Curated by
ChEMBL
Ligand
BDBM50242377
(CHEMBL448060 | isoimperatorin)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by spectrophotom...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
KEGG
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PC sid
Similars
In Depth
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Article
PubMed
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Target
Cholinesterase
(Equus caballus (Horse))
Ramkhamhaeng University
Curated by
ChEMBL
Ligand
BDBM50242377
(CHEMBL448060 | isoimperatorin)
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Affinity Data
IC50: 2.31E+4nM
Assay Description:
Inhibition of horse serum BChE after 2 mins by Ellman's reaction
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
KEGG
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
Sunchon National University
Curated by
ChEMBL
Ligand
BDBM50242377
(CHEMBL448060 | isoimperatorin)
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Affinity Data
IC50: 2.56E+4nM
Assay Description:
Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's metho...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
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ChEBI
CHEMBL
KEGG
PC cid
PC sid
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Article
PubMed
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Target
Amine oxidase [flavin-containing] B
(Homo sapiens (Human))
Sunchon National University
Curated by
ChEMBL
Ligand
BDBM50242377
(CHEMBL448060 | isoimperatorin)
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Affinity Data
IC50: >6.00E+4nM
Assay Description:
Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using benzylamine as substrate after 30 mins by spectrophoto...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Acetylcholinesterase
(Homo sapiens (Human))
Seoul National University
Curated by
ChEMBL
Ligand
BDBM50242377
(CHEMBL448060 | isoimperatorin)
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Affinity Data
IC50: 6.90E+4nM
Assay Description:
Inhibition of AChE by spectrophotometry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Beta-secretase 1
(Homo sapiens (Human))
Kinki University
Curated by
ChEMBL
Ligand
BDBM50242377
(CHEMBL448060 | isoimperatorin)
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Affinity Data
IC50: 2.44E+5nM
Assay Description:
Inhibition of human recombinant BACE1 after 60 mins by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
KEGG
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PC sid
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In Depth
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Article
PubMed
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Target
Beta-secretase 1
(Homo sapiens (Human))
Kinki University
Curated by
ChEMBL
Ligand
BDBM50242377
(CHEMBL448060 | isoimperatorin)
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Copy InChI
Affinity Data
IC50: 2.44E+5nM
Assay Description:
Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK as substrate after 60 mins by fluorescence quenching assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI