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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCytochrome P450 1B1(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503774(CHEMBL4444783)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCytochrome P450 1A1(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503774(CHEMBL4444783)
Affinity DataIC50:  525nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503774(CHEMBL4444783)
Affinity DataIC50:  667nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed