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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCytochrome P450 1B1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50278193(3-(pyridin-3-yl)-1-(2,3,4-trimethoxyphenyl)prop-2-...)
Affinity DataIC50:  137nMAssay Description:Inhibition of human liver CYP1B1 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using 7-ethoxyresorufin as substrate after 10 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50278193(3-(pyridin-3-yl)-1-(2,3,4-trimethoxyphenyl)prop-2-...)
Affinity DataIC50:  176nMAssay Description:Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50278193(3-(pyridin-3-yl)-1-(2,3,4-trimethoxyphenyl)prop-2-...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of human liver CYP1A1 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using 7-ethoxyresorufin as substrate after 10 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMO15-related protein kinase Pfmrk(Plasmodium falciparum)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50278193(3-(pyridin-3-yl)-1-(2,3,4-trimethoxyphenyl)prop-2-...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of His6x-tagged Plasmodium falciparum Pfmrk expressed in Escherichia coli by microtiter plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed