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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
17
hits in this display
Target
Cytochrome P450 1B1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
Ki: 3.70E+3nM
Assay Description:
Inhibition of CYP1B1 in human liver microsomes coexpressing recombinant human cytochrome P450 oxidoreductase using 7-ethoxyresorufin as substrate aft...
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Target
Neuraminidase
(Influenza A virus)
University of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
IC50: 1.37E+3nM
Assay Description:
Inhibition of Influenza A virus (A/Puerto Rico/8/1934(H1N1)) neuraminidase by chemiluminescence based assay
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Target
Neuraminidase
(Influenza A virus)
University of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
IC50: 3.04E+3nM
Assay Description:
Inhibition of Influenza A virus J/8178/09 neuraminidase by chemiluminescence based assay
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Target
Neuraminidase
(Influenza A virus)
University of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
IC50: 5.04E+3nM
Assay Description:
Inhibition of oseltamivir-resistant Influenza A virus H1N1 B/55/08 neuraminidase by chemiluminescence based assay
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Target
Neuraminidase
(Influenza A virus)
University of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
IC50: 5.04E+3nM
Assay Description:
Inhibition of Influenza A virus (A/Hong Kong/1/1968(H3N2)) neuraminidase by chemiluminescence based assay
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Target
Amine oxidase [flavin-containing] B
(Mus musculus)
Sunchon National University
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
IC50: 1.10E+4nM
Assay Description:
Inhibition of mouse MAO-B preincubated for 15 mins followed by addition of kynuramine as substrate measured after 30 mins by fluorometric analysis
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Target
Amine oxidase [flavin-containing] A
(Mus musculus)
Sunchon National University
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
IC50: 2.12E+4nM
Assay Description:
Inhibition of mouse MAO-A preincubated for 15 mins followed by addition of kynuramine as substrate measured after 30 mins by fluorometric analysis
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Target
Amine oxidase [flavin-containing] B
(Homo sapiens (Human))
Sunchon National University
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
IC50: 2.58E+4nM
Assay Description:
Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells preincubated for 10 mins followed by addition of benzylamine...
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Target
Amine oxidase [flavin-containing] A
(Homo sapiens (Human))
Sunchon National University
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
IC50: 3.12E+4nM
Assay Description:
Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells preincubated for 10 mins followed by addition of kynuramine ...
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Target
Sortase family protein
(Staphylococcus aureus)
TBA
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
IC50: 7.49E+4nM
Assay Description:
Inhibition of SiaTnTRI2-induced activation of CD69 high in human lymphocytes assessed as InsP3 production
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Target
Neuraminidase
(Influenza A virus)
University of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of Influenza A Jiangsu/10/2003 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assay
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Target
Neuraminidase
(Influenza A virus)
University of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of Influenza A Jinan/15/90 H3N2 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assay
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Target
Cytochrome P450 1A1
(Homo sapiens (Human))
University of Nottingham
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
IC50: <1.00E+5nM
Assay Description:
Inhibition of CYP1A1 by EROD assay
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Target
Neuraminidase
(Influenza A virus)
University of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assay
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Target
Proteasome subunit beta type-5
(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of chymotrypsin-like activity of purified human erythrocyte 20S proteasome assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as su...
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Target
Urease subunit beta
(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Jishou University
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
IC50: 2.00E+6nM
Assay Description:
Inhibition of Helicobacter pylori ATCC 43504 urease-mediated ammonia production preincubated for 1.5 hrs by indophenol method
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Target
Interleukin-2
(Homo sapiens (Human))
The Second People'S Hospital Of Fujian Provinc
Curated by
ChEMBL
Ligand
BDBM50021398
(CHEBI:18088 | FORMONONETIN | NSC-93360)
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Affinity Data
Kd: 5.47E+3nM
Assay Description:
Binding affinity to IL-2 (unknown origin)
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