Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM194228(US9200006, Ref Ex 9)
Affinity DataKi:  2.60nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM456056(US10723709, Reference Example 9 | US11312693, Ref ...)
Affinity DataKi:  2.60nMAssay Description:The recombinant cathepsin K can be expressed in a variety of commercially available expression systems including E coli, Pichia and Baculovirus syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM456056(US10723709, Reference Example 9 | US11312693, Ref ...)
Affinity DataKi:  2.60nMAssay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM456056(US10723709, Reference Example 9 | US11312693, Ref ...)
Affinity DataKi:  6.10E+3nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM456056(US10723709, Reference Example 9 | US11312693, Ref ...)
Affinity DataKi:  6.10E+3nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM194228(US9200006, Ref Ex 9)
Affinity DataKi:  6.10E+3nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent