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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50053608
(1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...)
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Affinity Data
Ki: 32nM
Assay Description:
Displacement of [3H]GR65630 from 5-HT3 receptor (unknown origin) expressed in mouse/rat NG108-15 cells after 30 mins by by liquid scintillation count...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
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Target
5-hydroxytryptamine receptor 3A/3B/3C/3D/3E
(Homo sapiens (Human))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50053608
(1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...)
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Affinity Data
Ki: 35nM
Assay Description:
Compound was tested for the inhibition of [3H]-GR-65,630 binding to 5-hydroxytryptamine 3 receptor expressed in NG 108-15 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Urokinase-type plasminogen activator
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50053608
(1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...)
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Affinity Data
Ki: 6.17E+4nM
Assay Description:
log1/Ki value was calculated against Urokinase-type plasminogen activator
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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Article
PubMed
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Target
Urokinase-type plasminogen activator
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50053608
(1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...)
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Affinity Data
Ki: 6.18E+4nM
Assay Description:
Inhibition against Urokinase-type plasminogen activator
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
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In Depth
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Article
PubMed
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Target
Serine protease 1
(Bos taurus (bovine))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50053608
(1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...)
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Affinity Data
Ki: 1.10E+6nM
Assay Description:
Inhibition against Trypsin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
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Ligand Info
CHEMBL
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In Depth
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Article
PubMed
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Target
Serine protease 1
(Bos taurus (bovine))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50053608
(1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...)
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Affinity Data
Ki: 1.10E+6nM
Assay Description:
Inhibition against Trypsin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
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Ligand Info
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Article
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Target
Plasminogen
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50053608
(1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...)
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Affinity Data
Ki: <1.00E+7nM
Assay Description:
Inhibition against human plasmin was determined at 0.5 mM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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In Depth
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Article
PubMed
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Target
Solute carrier family 22 member 3
(Homo sapiens (Human))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50053608
(1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...)
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Affinity Data
IC50: 7.60E+3nM
Assay Description:
Inhibition of human OCT3 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Solute carrier family 22 member 1
(Homo sapiens (Human))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50053608
(1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...)
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Affinity Data
IC50: 1.37E+4nM
Assay Description:
Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Solute carrier family 22 member 2
(Homo sapiens (Human))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50053608
(1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...)
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Affinity Data
IC50: 6.05E+4nM
Assay Description:
Inhibition of human OCT2 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI