Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50235077(CHEMBL4074920)Copy SMILESCopy InChI

Affinity DataIC50:  8.79E+3nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50235077(CHEMBL4074920)Copy SMILESCopy InChI

Affinity DataIC50: >2.00E+4nMAssay Description:Activity at human beta1 adrenergic receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50235077(CHEMBL4074920)Copy SMILESCopy InChI

Affinity DataIC50: >2.00E+4nMAssay Description:Activity at human beta2 adrenergic receptorMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50235077(CHEMBL4074920)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human Nav1.5 by electrophysiology methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50235077(CHEMBL4074920)Copy SMILESCopy InChI

Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50235077(CHEMBL4074920)Copy SMILESCopy InChI

Affinity DataEC50:  0.320nMAssay Description:Agonist activity at human beta3 adrenergic receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50235077(CHEMBL4074920)Copy SMILESCopy InChI

Affinity DataEC50:  251nMAssay Description:Inhibition of NET (unknown origin) expressed in HEK293 cells assessed as reduction in norepinephrine reuptakeMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI