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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Beta-secretase 1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50510976
(CHEMBL4560579)
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Affinity Data
IC50: 0.400nM
Assay Description:
Inhibition of BACE1 (unknown origin) using FRET peptide substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRE...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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PDB
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PDB
3D Structure (crystal)
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Target
Beta-secretase 1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50510976
(CHEMBL4560579)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20nM
Assay Description:
Inhibition of BACE in HEK293 cells harboring APP Swedish mutant assessed as reduction in amyloid beta 40 level measured after overnight incubation by...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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PDB
In Depth
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Article
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PDB
3D Structure (crystal)
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Target
Beta-secretase 2
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50510976
(CHEMBL4560579)
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Affinity Data
IC50: 19nM
Assay Description:
Inhibition of BACE2 (unknown origin) using FRET peptide substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRE...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-secretase 2
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50510976
(CHEMBL4560579)
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Copy InChI
Affinity Data
IC50: 569nM
Assay Description:
Inhibition of recombinant human BACE2 expressed in HEK293 cells co-transfected with N-terminal HA-tagged/C-terminal Myc tagged Mbeta chain of human P...
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Target Info
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In Depth
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Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50510976
(CHEMBL4560579)
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Affinity Data
IC50: 6.90E+3nM
Assay Description:
Inhibition of human ERG
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
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DrugBank
antibodypedia
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50510976
(CHEMBL4560579)
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Affinity Data
IC50: 2.00E+4nM
Assay Description:
Inhibition of CYP2D6 (unknown origin)
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Target Info
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50510976
(CHEMBL4560579)
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Affinity Data
IC50: 2.50E+4nM
Assay Description:
Inhibition of CYP2C9 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50510976
(CHEMBL4560579)
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Affinity Data
IC50: 2.70E+4nM
Assay Description:
Inhibition of CYP3A4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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Target
Cathepsin D
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50510976
(CHEMBL4560579)
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Affinity Data
IC50: 1.37E+5nM
Assay Description:
Inhibition of recombinant CatD (unknown origin) expressed in CHO cells using FRET peptide substrate preincubated for 1 hr followed by substrate addit...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC sid
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In Depth
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Article
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Target
Renin
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50510976
(CHEMBL4560579)
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Affinity Data
IC50: 6.78E+5nM
Assay Description:
Inhibition of renin (unknown origin)
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
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Target
Cathepsin E
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50510976
(CHEMBL4560579)
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Affinity Data
IC50: 1.38E+6nM
Assay Description:
Inhibition of cathepsin E (unknown origin)
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
antibodypedia
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PC cid
PC sid
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In Depth
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PubMed
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