Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 45 hits in this display
Histone deacetylase(Plasmodium falciparum (isolate 3D7))Dipartimento Di Chimica E Tecnologie Del Farmaco "Sapienza" Universit£
Curated by ChEMBL
IC50: 0.900nMAssay Description:Inhibition of HDAC3 in human DU-145 cells assessed as increase in histone H3 acetylation after 24 hrs by immunofluorescence microscopyMore data for this Ligand-Target Pair
IC50: 1.40nMAssay Description:Inhibition of HDAC1 in human DU-145 cells assessed as increase in histone H3 acetylation after 24 hrs by immunofluorescence microscopyMore data for this Ligand-Target Pair
IC50: 1.60nMAssay Description:Displacement of [3H]-acetylated histones from human HDAC1 transfected in HEK-293T cells incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
IC50: 3.90nMAssay Description:Displacement of [3H]-acetylated histones from human HDAC2 transfected in HEK-293T cells incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
IC50: 4.70nMAssay Description:Inhibition of HDAC2 in human DU-145 cells assessed as increase in histone H3 acetylation after 24 hrs by immunofluorescence microscopyMore data for this Ligand-Target Pair
IC50: 10nMAssay Description:Inhibition of HDAC8 in human DU-145 cells assessed as increase in histone H3 acetylation after 24 hrs by immunofluorescence microscopyMore data for this Ligand-Target Pair
IC50: 180nMAssay Description:Inhibition of HDAC6 in human DU-145 cells assessed as increase in histone H3 acetylation after 24 hrs by immunofluorescence microscopyMore data for this Ligand-Target Pair
IC50: 790nMAssay Description:Displacement of [3H]-acetylated histones from mouse HDAC6 transfected in HEK-293T cells incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
Protein Tat(Human immunodeficiency virus type 1 (isolate HXB2 ...)The Walter And Eliza Hall Institute For Medical Research
Curated by ChEMBL