Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBeta-secretase 2(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL

LigandBDBM50012646(CHEMBL3261056)Copy SMILESCopy InChI

Affinity DataKi:  17nMAssay Description:Inhibition of human BACE2 catalytic domain using QSY7-EISEVNLDAEFC-Eu-amide as substrate preincubated for 30 mins followed by substrate addition meas...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL

LigandBDBM50012646(CHEMBL3261056)Copy SMILESCopy InChI

Affinity DataKi:  27nMAssay Description:Inhibition of recombinant soluble human BACE1 catalytic domain using QSY7-EISEVNLDAEFC-Europium-amide as substrate preincubated for 30 mins followed ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI