Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
30
hits in this display
Target
Cannabinoid receptor 2
(Homo sapiens (Human))
Concordia University Wisconsin
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
Ki: 574nM
Assay Description:
Displacement of [3H]-CP55940 from recombinant human CB2 receptor expressed in Sf9 cell membranes co-expressing Galphai3beta1gamma2 measured after 90 ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2B6
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.30E+3nM
Assay Description:
Mixed inhibition of recombinant CYP2B6 (unknown origin) using coumarin as substrate in presence of NADPH-generating system by Lineweaver-burk plots a...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.40E+3nM
Assay Description:
Mixed inhibition of CYP2C19 (unknown origin) by measuring inhibition constant
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Cytochrome P450 1A1
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.60E+3nM
Assay Description:
Inhibition of human recombinant CYP1A1 preincubated with NADPH for 20 mins and measured after 30 min by Lineweaver-burk plots analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.80E+3nM
Assay Description:
Inhibition of CYP2D6 in human liver microsomes by measuring inhibition constant in presence of NADPH-generating system incubated for 20 mins
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Cannabinoid receptor 1
(Homo sapiens (Human))
Concordia University Wisconsin
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.47E+4nM
Assay Description:
Displacement of [3H]-CP55940 from recombinant human CB1 receptor expressed in Sf9 cell membranes co-expressing Galphai3beta1gamma2 measured after 90 ...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1A1
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 60nM
Assay Description:
Inhibition of recombinant CYP1A1 (unknown origin) preincubated with NADPH for 20 mins and measured after 30 min
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Transient receptor potential cation channel subfamily M member 8
(Rattus norvegicus (Rat))
Marshall University
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 900nM
Assay Description:
Antagonist activity at recombinant rat TRPM8 stably expressed in HEK293 cells assessed as inhibition of icilin-induced intracellular calcium level pr...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transient receptor potential cation channel subfamily M member 8
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 900nM
Assay Description:
Antagonist activity at TRPM8 (unknown origin) desensitization in presence of icilin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Transient receptor potential cation channel subfamily A member 1
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.30E+3nM
Assay Description:
Agonist activity at TRPA1 (unknown origin) channel desensitization in presence of isothiocyanate
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Transient receptor potential cation channel subfamily V member 4
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.90E+3nM
Assay Description:
Agonist activity at ionomycin-stimulated TRPV4 (unknown origin) channel desensitization in presence of 4alphaPDD
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.70E+3nM
Assay Description:
Mixed inhibition of CYP2C19 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Cytochrome P450 2B6
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.40E+3nM
Assay Description:
Mixed inhibition of recombinant CYP2B6 (unknown origin) using coumarin as substrate in presence of NADPH-generating system
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
Agonist activity at ionomycin-stimulated TRPV1 (unknown origin) channel desensitization in presence of capsaicin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.02E+4nM
Assay Description:
Inhibition of CYP2D6 in human liver microsomes in presence of NADPH-generating system incubated for 20 mins
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Diacylglycerol lipase-alpha
(Homo sapiens (Human))
Concordia University Wisconsin
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.66E+4nM
Assay Description:
Inhibition of recombinant human DAGLalpha expressed in COS7 cells using [14C]-oleoyl-2-arachidonoyl-glycerol as substrate measured after 20 mins by b...
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Diacylglycerol lipase-alpha
(Homo sapiens (Human))
Concordia University Wisconsin
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.66E+4nM
Assay Description:
Inhibition of human recombinant DAGLalpha expressed in African green monkey COS7 cells by beta counter analysis
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Transient receptor potential cation channel subfamily V member 3
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.50E+4nM
Assay Description:
Agonist activity at ionomycin-stimulated TRPV3 (unknown origin) channel desensitization in presence of carvacrol
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Transient receptor potential cation channel subfamily V member 2
(Homo sapiens)
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.10E+4nM
Assay Description:
Agonist activity at ionomycin-stimulated TRPV2 (unknown origin) channel desensitization in presence of lysophosphatidylcholine
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat))
Concordia University Wisconsin
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of FAAH in rat brain membranes using [14C]-AEA as substrate measured after 30 mins by scintillation counting method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
N-acylethanolamine-hydrolyzing acid amidase
(Homo sapiens (Human))
Concordia University Wisconsin
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.23E+4nM
Assay Description:
Inhibition of recombinant human NAAA expressed in HEK293 cells using [14C]-N-palmitoylethanolamine as substrate measured after 30 mins by beta-counti...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.60E+3nM
Assay Description:
Agonist activity at ionomycin-stimulated TRPV1 (unknown origin) activation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Transient receptor potential cation channel subfamily A member 1
(Rattus norvegicus)
Marshall University
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
EC50: 420nM
Assay Description:
Agonist activity at recombinant rat TRPA1 stably expressed in HEK293 cells assessed as increase in intracellular calcium release by Fluo-4AM dye base...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
G-protein coupled receptor 6
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.40E+3nM
Assay Description:
Binding affinity to human GPR6 expressed in HEK293 cells assessed as reduction in cAMP level incubated for 1 hr by HTRF assay
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Transient receptor potential cation channel subfamily V member 4
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
EC50: 900nM
Assay Description:
Agonist activity at ionomycin-stimulated TRPV4 (unknown origin) activation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Transient receptor potential cation channel subfamily V member 3
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.70E+3nM
Assay Description:
Agonist activity at ionomycin-stimulated TRPV3 (unknown origin) activation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Transient receptor potential cation channel subfamily A member 1
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
EC50: 420nM
Assay Description:
Agonist activity at TRPA1 (unknown origin) activation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Transient receptor potential cation channel subfamily V member 2
(Homo sapiens)
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
EC50: 7.30E+3nM
Assay Description:
Agonist activity at ionomycin-stimulated TRPV2 (unknown origin) activation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
G-protein coupled receptor 55
(Homo sapiens (Human))
Scientus Pharma
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
EC50: 400nM
Assay Description:
Binding affinity to human GPR55 expressed in HEK293 cells assessed as LPI-stimulated ERK1/2 phosphorylation
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Cannabinoid receptor 2
(Homo sapiens (Human))
Concordia University Wisconsin
Curated by
ChEMBL
Ligand
BDBM50532215
(CBD-V | CBDV | Cannabidivarin | GWP42006)
Copy SMILES
Copy InChI
Affinity Data
EC50: 13nM
Assay Description:
Positive allosteric modulation of JWH-133-induced agonist activity at wild type CB2 receptor (unknown origin) stably expressed in HEK293T cells asses...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI