Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL

LigandBDBM50240557(CHEMBL4065655)Copy SMILESCopy InChI

Affinity DataKi:  67nMAssay Description:Inhibition of recombinant human BACE1 (Ala8P to Ala326 residues) expressed in Escherichia coli BL21(DE3) using Arg-Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetBeta-secretase 2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL

LigandBDBM50240557(CHEMBL4065655)Copy SMILESCopy InChI

Affinity DataKi:  7.14E+3nMAssay Description:Inhibition of BACE2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL

LigandBDBM50240557(CHEMBL4065655)Copy SMILESCopy InChI

Affinity DataEC50:  19nMAssay Description:Inhibition of BACE1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI