Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Temple University School Of Pharmacy

Curated by ChEMBL

LigandBDBM50521248(CHEMBL4549145)Copy SMILESCopy InChI

Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using Mca-APP Swedish Lys-Met/Asn-Leu mutant-Dnp quencher as substrate measured at 30 mins interval ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 2(Homo sapiens (Human))
Temple University School Of Pharmacy

Curated by ChEMBL

LigandBDBM50521248(CHEMBL4549145)Copy SMILESCopy InChI

Affinity DataIC50:  275nMAssay Description:Inhibition of recombinant BACE2 (unknown origin) using Mca-APP Swedish Lys-Met/Asn-Leu mutant-Dnp quencher as substrate measured at 30 mins interval ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI