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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Beta-secretase 1
(Homo sapiens (Human))
Janssen Research & Development
Curated by
ChEMBL
Ligand
BDBM50510774
(CHEMBL4459963)
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Affinity Data
IC50: 9.60nM
Assay Description:
Inhibition of BACE1 in human SK-N-BE(2) cells expressing human APP695 assessed as reduction in amyloidbeta level incubated for 18 hrs by sandwich ELI...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-secretase 1
(Homo sapiens (Human))
Janssen Research & Development
Curated by
ChEMBL
Ligand
BDBM50510774
(CHEMBL4459963)
Copy SMILES
Copy InChI
Affinity Data
IC50: 76nM
Assay Description:
Inhibition of recombinant BACE1 (unknown origin) incubated for 145 mins by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-secretase 2
(Homo sapiens (Human))
Janssen Research & Development
Curated by
ChEMBL
Ligand
BDBM50510774
(CHEMBL4459963)
Copy SMILES
Copy InChI
Affinity Data
IC50: 170nM
Assay Description:
Inhibition of recombinant BACE2 (unknown origin) incubated for 145 mins by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI