Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Decaprenylphosphoryl-beta-D-ribose oxidase
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Soochow University
Curated by
ChEMBL
Ligand
BDBM50515570
(Macozinone | PBTZ-169 | PBTZ169)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of Mycobacterium tuberculosis H37Rv recombinant DprE1 expressed in Escherichia coli assessed as formation of resorufin using FPR as substr...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Decaprenylphosphoryl-beta-D-ribose oxidase
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Soochow University
Curated by
ChEMBL
Ligand
BDBM50515570
(Macozinone | PBTZ-169 | PBTZ169)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of Mycobacterium tuberculosis DprE1 expressed in Escherichia coli BL21 (DE3) cells assessed as formation of resorufin using FPR as substra...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College
Curated by
ChEMBL
Ligand
BDBM50515570
(Macozinone | PBTZ-169 | PBTZ169)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.77E+3nM
Assay Description:
Inhibition of CYP2C19 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College
Curated by
ChEMBL
Ligand
BDBM50515570
(Macozinone | PBTZ-169 | PBTZ169)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP3A4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College
Curated by
ChEMBL
Ligand
BDBM50515570
(Macozinone | PBTZ-169 | PBTZ169)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP1A2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College
Curated by
ChEMBL
Ligand
BDBM50515570
(Macozinone | PBTZ-169 | PBTZ169)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2C9 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College
Curated by
ChEMBL
Ligand
BDBM50515570
(Macozinone | PBTZ-169 | PBTZ169)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2D6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College
Curated by
ChEMBL
Ligand
BDBM50515570
(Macozinone | PBTZ-169 | PBTZ169)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.02E+5nM
Assay Description:
Inhibition of human ERG transfected in HEK293 cells by whole-cell patch clamp method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI