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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Beta-lactamase
(Enterobacter cloacae)
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50191388
((5R)(6Z)-6-(6,7-5H-dihydropyrazolo[5,1-b]-oxazin-2...)
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Affinity Data
IC50: 5nM
Assay Description:
Inhibition of Enterobacter cloacae AmpC
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Beta-lactamase TEM
(Escherichia coli)
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50191388
((5R)(6Z)-6-(6,7-5H-dihydropyrazolo[5,1-b]-oxazin-2...)
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Copy InChI
Affinity Data
IC50: 6nM
Assay Description:
Inhibition of Escherichia coli TEM1
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metallo-beta-lactamase type 2
(Bacteroides fragilis)
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50191388
((5R)(6Z)-6-(6,7-5H-dihydropyrazolo[5,1-b]-oxazin-2...)
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Affinity Data
IC50: 140nM
Assay Description:
Inhibition of Bacteroides fragilis CcrA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Imipenem-hydrolyzing beta-lactamase
(Enterobacter cloacae)
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50191388
((5R)(6Z)-6-(6,7-5H-dihydropyrazolo[5,1-b]-oxazin-2...)
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Copy InChI
Affinity Data
IC50: 413nM
Assay Description:
Inhibition of Enterobacter cloacae Imi1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI