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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50309872
(4-(6-Bromooxazolo[4,5-b]pyridin-2-yl)-1,4-diazabic...)
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Affinity Data
Ki: 2.08nM
Assay Description:
Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 3A
(Mus musculus (house mouse))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50309872
(4-(6-Bromooxazolo[4,5-b]pyridin-2-yl)-1,4-diazabic...)
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Affinity Data
Ki: 926nM
Assay Description:
Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50309872
(4-(6-Bromooxazolo[4,5-b]pyridin-2-yl)-1,4-diazabic...)
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Affinity Data
IC50: 779nM
Assay Description:
Agonist activity at human 5HT3 receptor expressed in human skin epithelial cells assessed as stimulation of calcium flux by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50309872
(4-(6-Bromooxazolo[4,5-b]pyridin-2-yl)-1,4-diazabic...)
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Copy InChI
Affinity Data
IC50: 2.30E+3nM
Assay Description:
Inhibition of human ERG
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI