Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCytochrome P450 1A1(Rattus norvegicus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50027776(4-Ethynyl Biphenyl | 4-Ethynyl-Biphenyl | CHEMBL37...)
Affinity DataKi:  270nMAssay Description:Mechanism based inhibition of rat cytochrome P450 CYP1A1 measured by 7-ethoxyresorufin O-deethylation (EROD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Rattus norvegicus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50027776(4-Ethynyl Biphenyl | 4-Ethynyl-Biphenyl | CHEMBL37...)
Affinity DataKi:  870nMAssay Description:Mechanism based inhibition of rat cytochrome P450 CYP1A2 measured by 7-methoxyresorufin O-demethylation (MROD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50027776(4-Ethynyl Biphenyl | 4-Ethynyl-Biphenyl | CHEMBL37...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of OGT (unknown origin) assessed as reduction in GlcNAc transfer to CKII peptide incubated for 60 mins by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed