Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50194202((1S,2R)-trans-2-[2-(cyclohexylmethylamino)ethyl]-1...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]Nalpha-methylhistamine form human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50194202((1S,2R)-trans-2-[2-(cyclohexylmethylamino)ethyl]-1...)
Affinity DataKi:  127nMAssay Description:Displacement of [3H]histamine form human H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50194202((1S,2R)-trans-2-[2-(cyclohexylmethylamino)ethyl]-1...)
Affinity DataIC50:  37nMAssay Description:Antagonist activity at human H3 receptor expressed in 293-EBNA cells assessed as inhibition of histamine agonist activity by luciferase reporter gene...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50194202((1S,2R)-trans-2-[2-(cyclohexylmethylamino)ethyl]-1...)
Affinity DataIC50:  1.50E+3nMAssay Description:Antagonist activity at human H4 receptor expressed in 293-EBNA cells assessed as inhibition of histamine agonist activity by luciferase reporter gene...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50194202((1S,2R)-trans-2-[2-(cyclohexylmethylamino)ethyl]-1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human H1 receptor expressed in 293-EBNA cells assessed as inhibition of histamine agonist activity by luciferase reporter gene...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50194202((1S,2R)-trans-2-[2-(cyclohexylmethylamino)ethyl]-1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human H2 receptor expressed in 293-EBNA cells assessed as inhibition of histamine agonist activity by luciferase reporter gene...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50194202((1S,2R)-trans-2-[2-(cyclohexylmethylamino)ethyl]-1...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human H1 receptor expressed in 293-EBNA cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50194202((1S,2R)-trans-2-[2-(cyclohexylmethylamino)ethyl]-1...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human H3 receptor expressed in 293-EBNA cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50194202((1S,2R)-trans-2-[2-(cyclohexylmethylamino)ethyl]-1...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human H4 receptor expressed in 293-EBNA cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50194202((1S,2R)-trans-2-[2-(cyclohexylmethylamino)ethyl]-1...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human H2 receptor expressed in 293-EBNA cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed