Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetCaspase-1(Homo sapiens (Human))
Depaul University

Curated by ChEMBL
LigandPNGBDBM50200551(CHEMBL3978901)
Affinity DataKi:  27nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DTT-activated caspase-1 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-5(Homo sapiens (Human))
Depaul University

Curated by ChEMBL
LigandPNGBDBM50200551(CHEMBL3978901)
Affinity DataKi:  59nMAssay Description:Inhibition of human recombinant DTT-activated caspase-5 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-4(Homo sapiens (Human))
Depaul University

Curated by ChEMBL
LigandPNGBDBM50200551(CHEMBL3978901)
Affinity DataKi:  306nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DTT-activated caspase-4 expressed in Escherichia coli using Ac-LEVD-AMC as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Depaul University

Curated by ChEMBL
LigandPNGBDBM50200551(CHEMBL3978901)
Affinity DataIC50:  95nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DTT-activated caspase-1 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-5(Homo sapiens (Human))
Depaul University

Curated by ChEMBL
LigandPNGBDBM50200551(CHEMBL3978901)
Affinity DataIC50:  254nMAssay Description:Inhibition of human recombinant DTT-activated caspase-5 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-4(Homo sapiens (Human))
Depaul University

Curated by ChEMBL
LigandPNGBDBM50200551(CHEMBL3978901)
Affinity DataIC50:  826nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DTT-activated caspase-4 expressed in Escherichia coli using Ac-LEVD-AMC as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed