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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
21
hits in this display
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Mcneil Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
Ki: 1.72nM
More data for this Ligand-Target Pair
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Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Mcneil Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
Ki: 2nM
Assay Description:
Effect of compound on Serotonin transporter uptake from rat cortex using [3H]citalopram as radioligand
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Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Mcneil Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
Ki: 2nM
Assay Description:
In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site
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Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Mcneil Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
Ki: 2.5nM
Assay Description:
In vitro binding affinity for serotonin reuptake sites in rat frontal cortex membranes by [3H]-paroxetine displacement.
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Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Mcneil Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5nM
More data for this Ligand-Target Pair
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Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Mcneil Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
Ki: 50.2nM
More data for this Ligand-Target Pair
Target Info
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Target
Norepinephrine transporter
(RAT)
Mcneil Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
Ki: 513nM
More data for this Ligand-Target Pair
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Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Mcneil Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
Ki: 794nM
More data for this Ligand-Target Pair
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Solvay Pharma
Curated by
ChEMBL
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
In vitro binding affinity at human cloned dopamine receptor D2 (long) stably expressed in CHO cells by [3H]-Spiperone displacement.
More data for this Ligand-Target Pair
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Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Mcneil Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
Copy SMILES
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Affinity Data
Ki: 1.04E+3nM
More data for this Ligand-Target Pair
Target Info
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Target
Norepinephrine transporter
(RAT)
Mcneil Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
Ki: 2.76E+3nM
More data for this Ligand-Target Pair
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Target
5-hydroxytryptamine receptor 3A
(RAT)
Eli Lilly
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
Ki: 3.24E+3nM
More data for this Ligand-Target Pair
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Target
Beta-arrestin-2
(Beef)
Eli Lilly
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
Ki: 3.24E+3nM
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine 1D receptor
(Bos taurus (Bovine))
Eli Lilly
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
Ki: 3.63E+3nM
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 1B
(Rattus norvegicus (Rat))
Eli Lilly
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
Ki: 4.47E+3nM
More data for this Ligand-Target Pair
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Eli Lilly
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
Copy SMILES
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Affinity Data
Ki: 9.12E+3nM
More data for this Ligand-Target Pair
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Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Mcneil Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
Copy SMILES
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Affinity Data
IC50: 10nM
Assay Description:
Inhibition of uptake of 5-HT in rat brain cortex
More data for this Ligand-Target Pair
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Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
IC50: 30nM
Assay Description:
In vivo inhibition of uptake of 5-HT in human platelets
More data for this Ligand-Target Pair
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Target
Transporter
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
IC50: 1.60E+3nM
Assay Description:
Inhibition of uptake of noradrenaline in rat brain hypothalamus
More data for this Ligand-Target Pair
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Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Mcneil Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.80E+4nM
Assay Description:
Inhibition of uptake of dopamine (DA) rat brain striatum
More data for this Ligand-Target Pair
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Target
Bile salt export pump
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50029150
(3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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