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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetHistone acetyltransferase GCN5(Saccharomyces cerevisiae S288c)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM47034(2,3-diphenyl-N-(phenylmethyl)-1,2,4-thiadiazol-2-i...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoethanolamine/phosphocholine phosphatase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM47034(2,3-diphenyl-N-(phenylmethyl)-1,2,4-thiadiazol-2-i...)
Affinity DataIC50:  2.59E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350105(N-benzyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...)
Affinity DataIC50:  5.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350105(N-benzyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...)
Affinity DataIC50:  5.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase GCN5(Saccharomyces cerevisiae S288c)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM47034(2,3-diphenyl-N-(phenylmethyl)-1,2,4-thiadiazol-2-i...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed