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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50278526
(4-((naphthalen-2-yloxy)methyl)piperidine | CHEMBL4...)
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Affinity Data
Ki: 311nM
Assay Description:
Displacement of [3H]granisetron from human 5HT3 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
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Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50278526
(4-((naphthalen-2-yloxy)methyl)piperidine | CHEMBL4...)
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Affinity Data
Ki: 3.80E+3nM
Assay Description:
Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50278526
(4-((naphthalen-2-yloxy)methyl)piperidine | CHEMBL4...)
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Affinity Data
IC50: 8nM
Assay Description:
Inhibition of radiolabeled serotonin reuptake at human SERT expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50278526
(4-((naphthalen-2-yloxy)methyl)piperidine | CHEMBL4...)
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Affinity Data
IC50: 1.80E+3nM
Assay Description:
Inhibition of radiolabeled noradrenaline reuptake at human NET expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50278526
(4-((naphthalen-2-yloxy)methyl)piperidine | CHEMBL4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >7.00E+3nM
Assay Description:
Inhibition of radiolabeled dopamine reuptake at human DAT expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI