Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetNischarin(RAT)
University Of Camerino

Curated by ChEMBL

LigandBDBM50193035(CHEMBL3961335)Copy SMILESCopy InChI

Affinity DataKi:  4nMAssay Description:Displacement of [125I]-p-iodoclonidine from I1 receptor imidazoline binding site in Sprague-Dawley rat kidney cell membranes after 30 mins by liquid ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL

LigandBDBM50193035(CHEMBL3961335)Copy SMILESCopy InChI

Affinity DataEC50:  2.51E+3nMAssay Description:Agonist activity at human alpha2b-AR expressed in CHO cells assessed as rate of acidification after 240 mins by cytosensor microphysiometric analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL

LigandBDBM50193035(CHEMBL3961335)Copy SMILESCopy InChI

Affinity DataEC50:  158nMAssay Description:Agonist activity at human alpha2c-AR expressed in CHO cells assessed as rate of acidification after 240 mins by cytosensor microphysiometric analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI