Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

TargetBeta-secretase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent

LigandBDBM259207(US9499502, 31a)Copy SMILESCopy InChI

Affinity DataKi:  5.00E+3nM ΔG°:  -30.8kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sid

In DepthDetails US Patent
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