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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Beta-secretase 1
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM186070
(US9163011, 24)
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Affinity Data
IC50: 240nM
pH: 4.5 T: 2°C
Assay Description:
Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 1 nM concentrations is incubated wi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Amyloid-beta precursor protein
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM186070
(US9163011, 24)
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Copy InChI
Affinity Data
IC50: 250nM
Assay Description:
Chinese hamster ovary cells are transfected with the human gene for amyloid precursor protein. The cells are plated at a density of 8000 cells/well i...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Beta-secretase 2
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM186070
(US9163011, 24)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.50E+3nM
pH: 4.5 T: 2°C
Assay Description:
Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 1 nM concentrations is incubated wi...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI