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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Shanghai University
Curated by
ChEMBL
Ligand
BDBM50204014
(CHEMBL3944424 | US10059667, Example 27)
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Affinity Data
EC50: 0.300nM
Assay Description:
Agonist activity at human GPR40 expressed in CHO cells coexpressing NFAT BLA assessed as increase in intracellular Ca2+ flux by fluo-4-AM dye based F...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Shanghai University
Curated by
ChEMBL
Ligand
BDBM50204014
(CHEMBL3944424 | US10059667, Example 27)
Copy SMILES
Copy InChI
Affinity Data
EC50: 7.60nM
T: 2°C
Assay Description:
The assay was performed in 96-well format. HEK cells stably expressing human GPR40 were plated to be 60-80% confluent within 72 h. After 72 h, the pl...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Shanghai University
Curated by
ChEMBL
Ligand
BDBM50204014
(CHEMBL3944424 | US10059667, Example 27)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.300nM
pH: 7.4 T: 2°C
Assay Description:
FLIPR (Fluorimetric Imaging Plate Reader, Molecular Devices) assays were performed to measure agonist-induced calcium mobilization of the stable clon...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI