Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50204014(CHEMBL3944424 | US10059667, Example 27)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells coexpressing NFAT BLA assessed as increase in intracellular Ca2+ flux by fluo-4-AM dye based F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50204014(CHEMBL3944424 | US10059667, Example 27)
Affinity DataEC50:  7.60nMT: 2°CAssay Description:The assay was performed in 96-well format. HEK cells stably expressing human GPR40 were plated to be 60-80% confluent within 72 h. After 72 h, the pl...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50204014(CHEMBL3944424 | US10059667, Example 27)
Affinity DataEC50:  0.300nMpH: 7.4 T: 2°CAssay Description:FLIPR (Fluorimetric Imaging Plate Reader, Molecular Devices) assays were performed to measure agonist-induced calcium mobilization of the stable clon...More data for this Ligand-Target Pair
In DepthDetails US Patent