Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097259((R)-2-(3-Cyclohexyl-propyl)-N*1*-[(S)-2,2-dimethyl...)
Affinity DataIC50:  120nMAssay Description:Concentration required to inhibit the catalytic domain Matrix metalloprotease-3 using Nagase fluorogenic as a substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097259((R)-2-(3-Cyclohexyl-propyl)-N*1*-[(S)-2,2-dimethyl...)
Affinity DataIC50:  120nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097259((R)-2-(3-Cyclohexyl-propyl)-N*1*-[(S)-2,2-dimethyl...)
Affinity DataIC50:  820nMAssay Description:Inhibition of human procollagen C-proteinase expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097259((R)-2-(3-Cyclohexyl-propyl)-N*1*-[(S)-2,2-dimethyl...)
Affinity DataIC50:  820nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097259((R)-2-(3-Cyclohexyl-propyl)-N*1*-[(S)-2,2-dimethyl...)
Affinity DataIC50:  920nMAssay Description:Concentration required to inhibit the catalytic domain Matrix metalloprotease-2 using Nagase fluorogenic as a substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097259((R)-2-(3-Cyclohexyl-propyl)-N*1*-[(S)-2,2-dimethyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097259((R)-2-(3-Cyclohexyl-propyl)-N*1*-[(S)-2,2-dimethyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed