Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL

LigandBDBM50122648((alphaS,betaR)(2-Chloro-4-{2-[2-hydroxy-2-(4-hydro...)Copy SMILESCopy InChI

Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of spontaneous contractions in isolated rat uterusMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-2 adrenergic receptor(Canis familiaris)
Kissei Pharmaceutical

Curated by ChEMBL

LigandBDBM50122648((alphaS,betaR)(2-Chloro-4-{2-[2-hydroxy-2-(4-hydro...)Copy SMILESCopy InChI

Affinity DataIC50:  6.46E+3nMAssay Description:Agonistic activity for Beta-2 adrenergic receptor was assessed by it's inhibitory effect on spontaneous contractions in isolated rat uterusMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL

LigandBDBM50122648((alphaS,betaR)(2-Chloro-4-{2-[2-hydroxy-2-(4-hydro...)Copy SMILESCopy InChI

Affinity DataEC50:  3.80nMAssay Description:Concentration required to effect a 50% relaxation of ferret detrusor basal toneMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI