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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Beta-secretase 1
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50273443
(CHEMBL4128145)
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Affinity Data
IC50: 1.08E+3nM
Assay Description:
Inhibition of human recombinant BACE1 catalytic domain in presence of FRET substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-secretase 1
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50273443
(CHEMBL4128145)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.08E+3nM
Assay Description:
Inhibition of human recombinant BACE1 catalytic domain using FRET substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Amyloid-beta precursor protein
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50273443
(CHEMBL4128145)
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Affinity Data
IC50: 1.16E+3nM
Assay Description:
Inhibition of wild type human APP751 expressed in CHO cells incubated for 24 hrs by immunoassay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-secretase 1
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50273443
(CHEMBL4128145)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.16E+3nM
Assay Description:
Inhibition of BACE1 (unknown origin) expressed in CHO cells co-expressing human APP751 assessed as decrease in amyloid beta 40 levels after 24 hrs by...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin D
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50273443
(CHEMBL4128145)
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Copy InChI
Affinity Data
IC50: 1.39E+5nM
Assay Description:
Inhibition of human cathepsin D using Mca-GKPILFFRLK(DNP)D-R-NH2 as a substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI