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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Amyloid-beta precursor protein
(Homo sapiens (Human))
Novartis Pharma
Curated by
ChEMBL
Ligand
BDBM50586753
(CHEMBL5089745)
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Affinity Data
IC50: 263nM
Assay Description:
Inhibition of wild type APP751 (unknown origin) expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Beta-secretase 1
(Homo sapiens (Human))
Novartis Pharma
Curated by
ChEMBL
Ligand
BDBM50586753
(CHEMBL5089745)
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Affinity Data
IC50: 696nM
Assay Description:
Inhibition of human recombinant BACE1 catalytic domain using FRET substrate with BACE-cleavable sequence
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-secretase 2
(Homo sapiens (Human))
Novartis Pharma
Curated by
ChEMBL
Ligand
BDBM50586753
(CHEMBL5089745)
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Affinity Data
IC50: 3.06E+3nM
Assay Description:
Inhibition of human recombinant BACE2 catalytic domain using FRET substrate with BACE-cleavable sequence
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin D
(Homo sapiens (Human))
Novartis Pharma
Curated by
ChEMBL
Ligand
BDBM50586753
(CHEMBL5089745)
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Affinity Data
IC50: 4.19E+4nM
Assay Description:
Inhibition of human Cathepsin D using Mca-GKPILFFRLK(DNP)D-R-NH2 as a substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI