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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
1
hit in this display
Target
Beta-secretase 2
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM190816
(US9181236, 78)
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Affinity Data
Ki: <20nM ΔG°: <-44.7kJ/mole
pH: 5.0 T: 2°C
Assay Description:
Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISE...
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Target Info
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antibodypedia
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Ligand Info
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US Patent
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