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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-4
(Rattus norvegicus (Rat))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50275302
((R)-3-((3-Methylazetidine-1-carbonyloxy)-1-methylp...)
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Affinity Data
Ki: 0.910nM
Assay Description:
Displacement of [3H]epibatidine from rat recombinant alpha4beta2 nAChR expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4
(Rattus norvegicus (Rat))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50275302
((R)-3-((3-Methylazetidine-1-carbonyloxy)-1-methylp...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.10nM
Assay Description:
Displacement of [3H]epibatidine from rat recombinant alpha4beta2 nAChR expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3
(Rattus norvegicus (Rat))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50275302
((R)-3-((3-Methylazetidine-1-carbonyloxy)-1-methylp...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 48nM
Assay Description:
Agonist activity at rat alpha-3-beta-4 nAChR expressed in HEK293 cells by FMP assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4
(Rattus norvegicus (Rat))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50275302
((R)-3-((3-Methylazetidine-1-carbonyloxy)-1-methylp...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 200nM
Assay Description:
Displacement of [3H]epibatidine from rat recombinant alpha-4-beta-4 nAChR expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4
(Rattus norvegicus (Rat))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50275302
((R)-3-((3-Methylazetidine-1-carbonyloxy)-1-methylp...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 260nM
Assay Description:
Displacement of [3H]epibatidine from rat recombinant alpha-4-beta-4 nAChR expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3
(Rattus norvegicus (Rat))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50275302
((R)-3-((3-Methylazetidine-1-carbonyloxy)-1-methylp...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.90E+4nM
Assay Description:
Displacement of [3H]epibatidine from rat recombinant alpha-3-beta-4 nAChR expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3
(Rattus norvegicus (Rat))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50275302
((R)-3-((3-Methylazetidine-1-carbonyloxy)-1-methylp...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.30E+4nM
Assay Description:
Displacement of [3H]epibatidine from rat recombinant alpha-3-beta-4 nAChR expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50275302
((R)-3-((3-Methylazetidine-1-carbonyloxy)-1-methylp...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+6nM
Assay Description:
Displacement of [3H]MLA from rat alpha-7 nAChR/mouse 5HT3A chimera expressed in human tsA-201 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50275302
((R)-3-((3-Methylazetidine-1-carbonyloxy)-1-methylp...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8.50E+4nM
Assay Description:
Agonist activity at human alpha-4-beta-2 nAChR expressed in Xenopus oocytes by two-electrode voltage clamp technique
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50275302
((R)-3-((3-Methylazetidine-1-carbonyloxy)-1-methylp...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >3.20E+5nM
Assay Description:
Agonist activity at human alpha-3-beta-4 nAChR expressed in Xenopus oocytes by two-electrode voltage clamp technique
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50275302
((R)-3-((3-Methylazetidine-1-carbonyloxy)-1-methylp...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >3.20E+5nM
Assay Description:
Agonist activity at human alpha-7 nAChR expressed in Xenopus oocytes by two-electrode voltage clamp technique
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI