Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 16 hits in this display
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
IC50: 0.200nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
IC50: 2.80nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
IC50: 4.90nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
IC50: 130nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
IC50: 135nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
IC50: 200nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
IC50: 440nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
IC50: 2.80E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
IC50: 4.90E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
IC50: 2.00E+4nMpH: 8.0Assay Description:The inhibitor solution is prepared by dissolving 3-5 mg of inhibitor in pH 2 solution (0.01 N HCl), such that the concentration of the solution is eq...More data for this Ligand-Target Pair
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
IC50: 1.30E+5nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
IC50: 1.35E+5nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
BDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
IC50: 4.40E+5nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair