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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Histamine H3 receptor
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM50472559
((S)-Alpha-Methylhistamine | CHEMBL11919)
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Affinity Data
Ki: 63nM
Assay Description:
Displacement of [3H]Nalpha-methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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Target
Histamine H3 receptor
(Rattus norvegicus (rat))
University Of Kuopio
Curated by
ChEMBL
Ligand
BDBM50472559
((S)-Alpha-Methylhistamine | CHEMBL11919)
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Affinity Data
Ki: 158nM
Assay Description:
Affinity for histamine H3 receptor in rat cerebral cortex.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC sid
In Depth
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Article
PubMed
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Target
Histamine H3 receptor
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM50472559
((S)-Alpha-Methylhistamine | CHEMBL11919)
Copy SMILES
Copy InChI
Affinity Data
Ki: 398nM
Assay Description:
Binding affinity in Nluc-hH3R assessed in HEK293T cells by NanoBRET binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM50472559
((S)-Alpha-Methylhistamine | CHEMBL11919)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.62E+3nM
Assay Description:
Binding affinity in Nluc-hH3R assessed in HEK293 cells by NanoBRET binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM50472559
((S)-Alpha-Methylhistamine | CHEMBL11919)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.98E+3nM
Assay Description:
Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM50472559
((S)-Alpha-Methylhistamine | CHEMBL11919)
Copy SMILES
Copy InChI
Affinity Data
EC50: 10nM
Assay Description:
Agonist activity at human histamine H3 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM50472559
((S)-Alpha-Methylhistamine | CHEMBL11919)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.26E+4nM
Assay Description:
Agonist activity at human histamine H4 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI