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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Estrogen receptor [D538G]
(Homo sapiens (Human))
Valorisation-Recherche, Limited Partnership
US Patent
Ligand
BDBM50370294
(Examorelin | HEXARELIN | US9708370, Hexareline)
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Affinity Data
IC50: 6.08nM
Assay Description:
GHS-R1a radioreceptor assay using LLCPK-1 membranes overexpressing GSH-R1a and radioiodinated (1-28) rat ghrelin as tracer.
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US Patent
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Target
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50370294
(Examorelin | HEXARELIN | US9708370, Hexareline)
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Affinity Data
IC50: 15.9nM
Assay Description:
Displacement of [125I]ghrelin expressed in in LLC-PK1 cells incubated for 1 hr by gamma counting method
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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In Depth
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Article
PubMed
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Target
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50370294
(Examorelin | HEXARELIN | US9708370, Hexareline)
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Affinity Data
IC50: 18nM
Assay Description:
Binding affinity towards human pituitary Growth hormone secretagogue receptor using [125I][Tyr4]-ghrelin as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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PC sid
Similars
In Depth
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Article
PubMed
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Target
Platelet glycoprotein 4
(Rattus norvegicus)
Universit£
Curated by
ChEMBL
Ligand
BDBM50370294
(Examorelin | HEXARELIN | US9708370, Hexareline)
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Affinity Data
IC50: 1.56E+3nM
Assay Description:
Inhibition of photoactivatable [125I]-Tyr-Bpa-Ala-hexarelin binding to CD36 in Sprague-Dawley rat heart membranes after 60 mins by SDS-PAGE analysis
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PC sid
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Article
PubMed
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Target
Platelet glycoprotein 4
(Rattus norvegicus)
Universit£
Curated by
ChEMBL
Ligand
BDBM50370294
(Examorelin | HEXARELIN | US9708370, Hexareline)
Copy SMILES
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Affinity Data
IC50: 2.08E+3nM
Assay Description:
Displacement of photoactivatable [125I]-Tyr-Bpa-Ala-Hexarelin from CD36 in Sprague-Dawley rat cardiac membranes incubated for 60 mins by densitometry
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet glycoprotein 4
(Rattus norvegicus)
Universit£
Curated by
ChEMBL
Ligand
BDBM50370294
(Examorelin | HEXARELIN | US9708370, Hexareline)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.97E+3nM
pH: 7.3
Assay Description:
Competition experiments were performed by incubating 50 μg of LLC-PK1 membranes expressing human GHS-R1a with 15 fmol of 125I-Ghrelin and increa...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Platelet glycoprotein 4
(Rattus norvegicus)
Universit£
Curated by
ChEMBL
Ligand
BDBM50370294
(Examorelin | HEXARELIN | US9708370, Hexareline)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.33E+3nM
pH: 7.3
Assay Description:
Competition experiments were performed by incubating 50 μg of LLC-PK1 membranes expressing human GHS-R1a with 15 fmol of 125I-Ghrelin and increa...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI