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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50049479
((S)-6-Amino-2-{(R)-2-[(S)-2-{(S)-2-[(R)-2-[(S)-2-a...)
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Affinity Data
Ki: 6nM
Assay Description:
Binding Affinity of the compound against Growth hormone secretagogue receptor of swine using [35S]-MK-0677 as radioligand
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Target
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50049479
((S)-6-Amino-2-{(R)-2-[(S)-2-{(S)-2-[(R)-2-[(S)-2-a...)
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Affinity Data
IC50: 6.08nM
Assay Description:
Displacement of [125I]ghrelin expressed in in LLC-PK1 cells incubated for 1 hr by gamma counting method
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Target
Platelet glycoprotein 4
(Rattus norvegicus)
Universit£
Curated by
ChEMBL
Ligand
BDBM50049479
((S)-6-Amino-2-{(R)-2-[(S)-2-{(S)-2-[(R)-2-[(S)-2-a...)
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Affinity Data
IC50: 1.82E+3nM
Assay Description:
Displacement of photoactivatable [125I]-Tyr-Bpa-Ala-Hexarelin from CD36 in Sprague-Dawley rat cardiac membranes incubated for 60 mins by densitometry
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Target Info
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Target
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50049479
((S)-6-Amino-2-{(R)-2-[(S)-2-{(S)-2-[(R)-2-[(S)-2-a...)
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Affinity Data
IC50: 6.00E+3nM
Assay Description:
Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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In Depth
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Article
PubMed
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Target
Growth hormone secretagogue receptor type 1
(Rattus norvegicus)
Novo Nordisk
Curated by
ChEMBL
Ligand
BDBM50049479
((S)-6-Amino-2-{(R)-2-[(S)-2-{(S)-2-[(R)-2-[(S)-2-a...)
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Affinity Data
EC50: 1.70nM
Assay Description:
Tested for GH-releasing property using classical rat pituitary cell assay
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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PubMed
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Target
Growth hormone secretagogue receptor type 1
(Rattus norvegicus)
Novo Nordisk
Curated by
ChEMBL
Ligand
BDBM50049479
((S)-6-Amino-2-{(R)-2-[(S)-2-{(S)-2-[(R)-2-[(S)-2-a...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 10nM
Assay Description:
In vitro growth hormone release was determined in rat pituitary cell assay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI