Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCathepsin K(Homo sapiens (Human))
Gsk

LigandPNGBDBM19793((2S)-1-(5,6-dichloro-1H-1,3-benzodiazol-1-yl)-3,3-...)
Affinity DataIC50:  1.40nMpH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gsk

LigandPNGBDBM19793((2S)-1-(5,6-dichloro-1H-1,3-benzodiazol-1-yl)-3,3-...)
Affinity DataIC50:  7.90nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gsk

LigandPNGBDBM19793((2S)-1-(5,6-dichloro-1H-1,3-benzodiazol-1-yl)-3,3-...)
Affinity DataIC50:  38nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Gsk

LigandPNGBDBM19793((2S)-1-(5,6-dichloro-1H-1,3-benzodiazol-1-yl)-3,3-...)
Affinity DataIC50:  71nMpH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed