Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 13 hits in this display
BDBM148176(US8962616, 22 | US8962616, 4)
BDBM148176(US8962616, 22 | US8962616, 4)
BDBM148176(US8962616, 22 | US8962616, 4)
IC50: 89nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
BDBM148176(US8962616, 22 | US8962616, 4)
IC50: 103nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing wild type human APP695 assessed as colorimetric reaction by Whole cell assayMore data for this Ligand-Target Pair
BDBM148176(US8962616, 22 | US8962616, 4)
BDBM148176(US8962616, 22 | US8962616, 4)
IC50: 1.40E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
BDBM148176(US8962616, 22 | US8962616, 4)
BDBM148176(US8962616, 22 | US8962616, 4)
BDBM148176(US8962616, 22 | US8962616, 4)
BDBM148176(US8962616, 22 | US8962616, 4)
BDBM148176(US8962616, 22 | US8962616, 4)
BDBM148176(US8962616, 22 | US8962616, 4)
BDBM148176(US8962616, 22 | US8962616, 4)