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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50007403
(1-(2-pyrimidyl)piperazine | 1-PP | 2-Piperazin-1-Y...)
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Affinity Data
Ki: 1.41E+3nM
Assay Description:
Evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat brain
More data for this Ligand-Target Pair
Target Info
PDB
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50007403
(1-(2-pyrimidyl)piperazine | 1-PP | 2-Piperazin-1-Y...)
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Copy InChI
Affinity Data
Ki: 1.41E+3nM
Assay Description:
Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacement
More data for this Ligand-Target Pair
Target Info
PDB
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PubMed
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Target
5-hydroxytryptamine receptor 3A
(RAT)
Virginia Commonwealth University
Curated by
PDSP K
i
Database
Ligand
BDBM50007403
(1-(2-pyrimidyl)piperazine | 1-PP | 2-Piperazin-1-Y...)
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Affinity Data
Ki: 4.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
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Ligand Info
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In Depth
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Target
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50007403
(1-(2-pyrimidyl)piperazine | 1-PP | 2-Piperazin-1-Y...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity of the compound towards sigma receptor in guinea pig brain membranes using [3H]-DTG as radioligand
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Target Info
PDB
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antibodypedia
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Target
Replicase polyprotein 1ab
(2019-nCoV)
Cornell University
Ligand
BDBM50007403
(1-(2-pyrimidyl)piperazine | 1-PP | 2-Piperazin-1-Y...)
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Affinity Data
IC50: 2.52E+3nM
Assay Description:
IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
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Similars
In Depth
Details
PubMed
Copy BDB DOI